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A tool for assessing the quality of multiple sequence alignments
Pelikánová, Veronika ; Maděránková, Denisa (referee) ; Škutková, Helena (advisor)
This thesis is dealing with quality assessment of multiple sequence alignments. It contains literature review of public available tools of multiple sequence alignments. The main part of this thesis focuses on the program on quality assessment of multiple sequence alignments (created with the help of various tools, using different settings, etc.). The program has a graphical user interface created in Matlab and is enclosed together with a set of nucleotide and protein sequences compiled for program testing and aplication. Last but not least, the thesis contains the assessment of public available tools resulting from program outputs.
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Methods for multialignment of nucleotide sequences
Trněný, Ondřej ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
To be able to understand characteristics and purpose of biological sequences correctly, it is crucial to have a possibility to sort and compare them. Because of this need and to extend existing knowledge pool, numerous methods were proposed. Especially in field of multiple sequences alignment. Methods for multiple sequences alignment may provide various valuable information about sequences which failed to show enough similarity in pairwise alignment. According to this, several algorithms were implemented in various computer applications which provide a way to analyse huge sets of data. One of those, the progressive alignment algorithm, is implemented as a part of this thesis
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A tool for assessing the quality of multiple sequence alignments
Pelikánová, Veronika ; Maděránková, Denisa (referee) ; Škutková, Helena (advisor)
This thesis is dealing with quality assessment of multiple sequence alignments. It contains literature review of public available tools of multiple sequence alignments. The main part of this thesis focuses on the program on quality assessment of multiple sequence alignments (created with the help of various tools, using different settings, etc.). The program has a graphical user interface created in Matlab and is enclosed together with a set of nucleotide and protein sequences compiled for program testing and aplication. Last but not least, the thesis contains the assessment of public available tools resulting from program outputs.
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Methods for multialignment of nucleotide sequences
Trněný, Ondřej ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
To be able to understand characteristics and purpose of biological sequences correctly, it is crucial to have a possibility to sort and compare them. Because of this need and to extend existing knowledge pool, numerous methods were proposed. Especially in field of multiple sequences alignment. Methods for multiple sequences alignment may provide various valuable information about sequences which failed to show enough similarity in pairwise alignment. According to this, several algorithms were implemented in various computer applications which provide a way to analyse huge sets of data. One of those, the progressive alignment algorithm, is implemented as a part of this thesis
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